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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR2
All Species:
19.7
Human Site:
S461
Identified Species:
33.33
UniProt:
Q16832
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16832
NP_001014796.1
855
96736
S461
F
N
N
N
R
S
S
S
P
S
E
Q
G
S
N
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
R475
I
N
N
R
P
G
P
R
E
P
P
P
Y
Q
E
Rhesus Macaque
Macaca mulatta
XP_001118206
855
96702
S461
F
N
N
N
R
S
S
S
P
S
E
Q
E
S
N
Dog
Lupus familis
XP_536144
849
95798
S455
F
N
N
N
R
S
S
S
P
S
E
Q
E
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q62371
854
96464
S461
F
N
N
N
R
S
S
S
P
S
E
Q
E
S
N
Rat
Rattus norvegicus
Q63474
910
101146
R476
I
N
N
R
P
G
P
R
E
P
P
P
Y
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
S510
N
H
H
R
R
S
A
S
P
S
E
Q
G
S
N
Chicken
Gallus gallus
Q91987
818
91718
I413
T
T
N
N
S
N
Q
I
T
S
P
D
V
S
N
Frog
Xenopus laevis
O73798
1358
153845
N758
S
T
T
E
D
F
S
N
F
S
D
S
E
R
D
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
V496
N
N
N
S
P
S
S
V
P
S
E
Q
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
I336
F
I
I
I
F
A
I
I
L
F
K
R
R
T
I
Honey Bee
Apis mellifera
XP_392450
898
100991
S470
L
V
S
P
Q
Y
K
S
T
Y
A
I
V
A
T
Nematode Worm
Caenorhab. elegans
NP_508572
797
90284
T429
A
K
R
E
I
L
L
T
I
D
G
N
T
I
K
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
T494
N
N
C
P
T
I
A
T
M
T
T
V
P
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
99.3
96.4
N.A.
95.9
52.8
N.A.
80.1
27.1
21
74.5
N.A.
24.3
30.2
32.8
39.8
Protein Similarity:
100
66
99.5
97.8
N.A.
97.3
66.1
N.A.
85.8
42.8
34.3
82.6
N.A.
41.9
48.7
52
55
P-Site Identity:
100
13.3
93.3
93.3
N.A.
93.3
13.3
N.A.
66.6
33.3
13.3
60
N.A.
6.6
6.6
0
13.3
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
93.3
13.3
N.A.
86.6
40
33.3
73.3
N.A.
33.3
26.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
15
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
8
8
0
0
8
% D
% Glu:
0
0
0
15
0
0
0
0
15
0
43
0
36
0
15
% E
% Phe:
36
0
0
0
8
8
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
0
0
0
0
8
0
15
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
8
8
8
8
8
8
15
8
0
0
8
0
8
8
% I
% Lys:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
8
% K
% Leu:
8
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
22
58
58
36
0
8
0
8
0
0
0
8
0
0
43
% N
% Pro:
0
0
0
15
22
0
15
0
43
15
22
15
8
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
0
0
43
0
15
0
% Q
% Arg:
0
0
8
22
36
0
0
15
0
0
0
8
8
8
8
% R
% Ser:
8
0
8
8
8
43
43
43
0
58
0
8
0
58
8
% S
% Thr:
8
15
8
0
8
0
0
15
15
8
8
0
8
8
8
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
8
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _